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J Parkinsons Dis ; 11(3): 971-992, 2021.
Article in English | MEDLINE | ID: covidwho-1201362

ABSTRACT

Sleep disturbances are among the common nonmotor symptoms in patients with Parkinson's disease (PD). Sleep can be disrupted by nocturnal motor and nonmotor symptoms and other comorbid sleep disorders. Rapid eye movement sleep behavior disorder (RBD) causes sleep-related injury, has important clinical implications as a harbinger of PD and predicts a progressive clinical phenotype. Restless legs syndrome (RLS) and its related symptoms can impair sleep initiation. Excessive daytime sleepiness (EDS) is a refractory problem affecting patients' daytime activities. In particular, during the COVID-19 era, special attention should be paid to monitoring sleep problems, as infection-prevention procedures for COVID-19 can affect patients' motor symptoms, psychiatric symptoms and sleep. Therefore, screening for and managing sleep problems is important in clinical practice, and the maintenance of good sleep conditions may improve the quality of life of PD patients. This narrative review focused on the literature published in the past 10 years, providing a current update of various sleep disturbances in PD patients and their management, including RBD, RLS, EDS, sleep apnea and circadian abnormalities.


Subject(s)
Disorders of Excessive Somnolence , Parkinson Disease , REM Sleep Behavior Disorder , Restless Legs Syndrome , Sleep Apnea Syndromes , Sleep Disorders, Circadian Rhythm , COVID-19 , Disorders of Excessive Somnolence/diagnosis , Disorders of Excessive Somnolence/etiology , Disorders of Excessive Somnolence/therapy , Humans , Parkinson Disease/complications , Parkinson Disease/diagnosis , Parkinson Disease/therapy , REM Sleep Behavior Disorder/diagnosis , REM Sleep Behavior Disorder/etiology , REM Sleep Behavior Disorder/therapy , Restless Legs Syndrome/diagnosis , Restless Legs Syndrome/etiology , Restless Legs Syndrome/therapy , Sleep Apnea Syndromes/diagnosis , Sleep Apnea Syndromes/etiology , Sleep Apnea Syndromes/therapy , Sleep Disorders, Circadian Rhythm/diagnosis , Sleep Disorders, Circadian Rhythm/etiology , Sleep Disorders, Circadian Rhythm/therapy
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